The NFL Injury Wire: Week 5

Every injury that matters on Sunday, newest first. Each entry covers what happened, who steps in, and our read on the fantasy impact.

Sunday morning update: inactives for the early games

Ja'Marr Chase and Tee Higgins (CIN)will both play against Miami, per ESPN's Adam Schefter, and both were full participants in Friday's practice. Start both. Ja'Marr Chase and Tee Higgins go back to their normal roles, and Dohnte Meyers drops back to a depth role.

Justin Jefferson (MIN) is active, but Jordan Addison (hamstring) and newly signed Odell Beckham Jr. are inactive. Justin Jefferson should see heavy volume, and T.J. Hockenson is the other beneficiary. Minnesota is also without left tackle Christian Darrisaw (concussion).

Jayden Daniels (WAS)is active against the Giants and wearing a brace on his non-throwing arm. NFL Network's Ian Rapoport says he's "not 100 percent." Marcus Mariota and Stefon Diggs are out, and Terry McLaurin was questionable, so check the inactive list. Start Jayden Daniels, and ignore Athan Kaliakmanis.

Ashton Jeanty (LV)is active after missing Friday's practice with his ankle and a plantar fasciitis flare-up. Ian Rapoport reported he was hopeful to play, and Las Vegas elevated a running back as insurance, so his workload is a question. Ashton Jeanty is still a start, but expect fewer touches early. New England is missing four cornerbacks and Mack Hollins, which helps the Raiders' passing game more than the run.

Saquon Barkley and DeVonta Smith (PHI) are out in London, along with edge rusher Jonathan Greenard. Will Shipley leads the backfield, and ESPN says to avoid him if you can. Dallas Goedert figures to be the Eagles' most-targeted receiver.

Alvin Kamara (NO)is active and should be the Saints' lead back, and Chris Olave carries no designation. Alvin Kamara needs catches and touchdowns to pay off, so he's a flex, not a lock.

Kyle Monangai (CHI) is out, so D'Andre Swift leads the Bears' backfield with Tyson Bagent at quarterback. Breece Hall is out for the Jets, and Braelon Allen leads theirs.

Still open for the late games

Ladd McConkey (LAC)is questionable, but Schefter reports he isn't expected to play after missing every practice with his foot injury. Tre Harris and Oronde Gadsden would see more targets. The Chargers' line is down Rashawn Slater (injured reserve), Joe Alt, Trevor Penning and Kayode Awosika, so Herbert has little time to throw.

Marvin Harrison Jr. (ARI)was told he'll be inactive against Detroit while Arizona finalizes a trade, per Schefter and Rapoport. Michael Wilson stays Arizona's top receiver.

Lamar Jackson (BAL)is out for Sunday night, so Tyler Huntley starts. Zay Flowers (foot) is questionable, and Baltimore is also without center Cam Jurgens (concussion) and edge Trey Hendrickson (finger). Atlanta's left tackle Jake Matthews (groin) is also questionable.

Mike Evans (SF) will play against Seattle, and Nick Bosa and Kyle Juszczyk are out. Aaron Donald is set to play Monday night after upgrading to a full practice Friday.